When creating a CNC programming design for acrylic machining processing, there are a few key considerations to keep in mind. 1ST Tool Selection: Choose the appropriate cutting tools for acrylic machining. Solid carbide end mills are often a good choice for cutting acrylic. 2ND Cutting Speeds and Feeds: Determine the optimal cutting speeds and feeds for the specific type of acrylic you are machining. This will help ensure smooth cutting and prevent overheating. 3RD Toolpath Strategy: Plan an efficient toolpath strategy to minimize tool changes and reduce machining time. 4TH Clamping and Fixturing: Secure the acrylic workpiece properly to prevent vibration and movement during machining.Toolpath Simulation: Before executing the CNC program, it's essential to simulate the toolpath using CAM software to check for any potential issues and optimize the machining process. 5TH Cooling and Chip Evacuation: Consider using coolants or air blasts to keep the cutting area cool and clear acrylic chips effectively.It's important to follow safety guidelines and use proper ventilation when machining acrylic due to the potential for fumes. Additionally, always test CNC program on a scrap piece of acrylic before machining the final workpiece to ensure the settings are correct and the quality of the cut meets your requirements.